Neutral. Still highly reliant on Keytruda but gives detailed pipeline which has so far assuaged the rating agencies and aims to cut $3bn of costs by 2027. Lower end of EPS range is upped which may be taken well.
• Sales $15.8bn down 2% yoy but in-line with estimates.
• Keytruda is still the dominant seller @ 50% of revenue.
• Non-GAAP net income $5,366 down 6% cfx; -8% nominal.
• Gross Margin 77.5% vs 76.8% yoy. Favourable product mix helped.
• R&D $4bn was +16% on license agreement with Hengrui.
• Gardasil (HPV vaccine) $1.13bn down 55% and 7% below estimates.
• Verona $10bn acquisition to close 4Q25.
• FY25 full year sales expected at $64.3bn-65.3bn mid-point more or less unchanged from $64.1-65.6bn prior. Outlook ex-Verona.
• Non-GAAP EPS $8.87-8.97 from $8.82-8.97 raising lower end.
• Embarking on multiyear cost-cutting plan. Aims to cut $3bn annual costs by YE27.
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Treasury reported Friday that as of Jun 25 it had $130B in remaining "extraordinary" measures (of a total $378B available) to ward off an "x-date" of running out of resources before defaulting. That's the highest in 2 weeks.

The Cleveland and Dallas Fed's median PCE metrics showed a notable drop in May. All indices suggest PCE inflation running above 2%, and higher than the actual core and headline PCE measures, but pressures appear to have cooled from a pickup in the early months of the year.


USDCAD has pulled back from its recent highs. The primary downtrend remains intact and short-term gains appear to have been corrective. Key support and the bear trigger has been defined at 1.3540, the Jun 16 low. Clearance of this price point would resume the downtrend. Any reversal higher would instead signal scope for a stronger retracement. Pivot resistance to monitor is at the 50-day EMA, at 1.3803.